Summer Thoughts : Meditation

https://digitalcommons.library.umaine.edu/mmb-ps/2799/thumbnail.jp

Let \u27Er Go! : March

https://digitalcommons.library.umaine.edu/mmb-ps/1978/thumbnail.jp

Aloha Oe : Hawaiian Waltz

https://digitalcommons.library.umaine.edu/mmb-ps/2042/thumbnail.jp

Autumn Leaves : Reverie

https://digitalcommons.library.umaine.edu/mmb-ps/1379/thumbnail.jp

Aloha Oe Waltzes

https://digitalcommons.library.umaine.edu/mmb-ps/2043/thumbnail.jp

Summer Thoughts

Illustration of woman holding roseshttps://scholarsjunction.msstate.edu/cht-sheet-music/7652/thumbnail.jp

Can a Digital Therapy Using Sound and Light Reset the Balance of Alzheimer’s Disease?

Alzheimer’s disease (AD) is a degenerative cognition-declining disease with no clear understanding of the underlying mechanisms. Currently, no effective therapeutics are available for AD. Amyloid-β (A-β) plaques and tau tangles were considered as the contributing factors to the development of AD. In contrast, controversial exists due to efforts focusing on A-β as a pharmacological therapeutic target was failed. Emerging evidence appeared for the external stimuli applied through vision (LED) and hearing (~40Hz) to certain intensity to dementia subjects with promising results such as reducing A-β and tau tangles in the brain tissue, increasing the brain volume reducing the decline of daily activities and mental status. This optogenetic and sound-derived digital therapeutic maneuver provides a striking way for conquering the development of AD